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Develop and improve products. List of Partners vendors. Hoodia gordonii , or Bushman's hat, is a succulent herb from South Africa. Since the early s, it has been promoted as a safe and effective appetite suppressant useful for weight loss. Some alternative practitioners believe it can also treat indigestion and mild gastrointestinal infections.

It may have other medicinal properties as well. To date, though, there is little evidence backing any benefits of hoodia. This article looks at the research behind claims about hoodia, its possible dangers, how to use it, and what to look for when buying it.

For centuries, the nomadic San people of South Africa have gnawed on hoodia while traveling through the desert.

They believe the succulent blocks hunger and boosts energy. By , the CSIR isolated a steroid sugar believed responsible. They named it P Nearly 20 years later, pharmaceutical giant Pfizer bought the rights to P They planned to make a weight-loss supplement but never did. Pfizer then released the rights and other manufacturers started making P57 products. Interestingly, a review of studies said it takes a lot of hoodia to reduce appetite. Authors also said that weight loss is actually a side effect of the herb.

Today, numerous hoodia supplements are sold. Early research suggests Hoodia may do the following, but more research is needed:. Despite centuries' worth of use to suppress appetite and boost energy, hoodia has not been proven to be useful for these or any other purposes. Hoodia is considered safe at low doses. However, at appetite-affecting doses it may cause:. Hoodia may also suppress thirst along with appetite. That raises concerns about dehydration.

By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Health Tools. Alternative Health. By Elizabeth Harrell. Reviewed: November 15, Hoodia Gordonii made headlines as a major weight loss miracle drug, but how safe is it really?

Even though many companies are making significant profits off of hoodia product sales, it has not been approved by the Food and Drug Administration. Since it is sold as a dietary supplement, FDA approval is not required to sell the product in the United States. Use the following guide to learn about the dangers of this miracle weight loss drug as well as the differenet types of hoodia that are available.

What is Hoodia Gordonii? Hoodia is a stem succulent, somewhat like a cactus, grown in South African desert regions. The San use hoodia for a variety of medicinal purposes, but most often, they chew it to avoid getting hungry and thirsty during extended hunting trips.

There are twenty different species of hoodia, but only hoodia gordonii appears to have the active ingredient p57, which provides the effects of an appetite suppressant. The South African government gained a patent for p57 and licensed it to a pharmaceutical company, Phytopharm. Later, it was determined that hoodia was not economically feasible for mass production, particularly due to the inability to effectively grow it anywhere except the African desert.

Case Studies. For example, one such study determined that taking the plant led not only led to the loss of body fat tissue but also muscle mass. This is undesirable, as muscles help maintain a healthy body There were no significant differences in body weight or food intake between those who received 1. Hoodia is mostly used as a weight loss supplement. In the only human study with the plant, the intake of purified hoodia extract reportedly caused numerous side effects, including nausea, dizziness, vomiting, and skin reactions It also caused a significant rise in heart rate and blood pressure 4 , Given the overall lack of information, taking the supplement for weight loss is not recommended, especially for pregnant and breastfeeding women.

Additionally, people taking medications for blood sugar control and heart or liver disease should steer clear of the supplement, as it may interfere with their treatments. Consuming hoodia may cause unwanted side effects, including nausea, dizziness, vomiting, skin reactions, elevated heart rate, and high blood pressure. More research is needed to determine a safe dose, if any. Its intake by nomadic hunter-gatherers who reportedly use it to suppress hunger during long hunts led to its popularity and widespread commercialization as a weight loss supplement.

However, little scientific evidence has been conducted in humans to support this effect, and the available research has shown a wide range of unwanted side effects.